August 2012 - New Publication
The work of Courtois et al., a collaboration with Takashi Hiragi group at EMBL, focusing on the meiosis to mitosis transition in early mouse embryonic stages, has been just published in the "Journal of Cell Biology" and is also among the recent "Research Highlight" in the "Nature...
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.
Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R.
Nat Cell Biol. 2012 Jun 3.
6th July 2012 - We offer a fun and interative presentation of the lab members and their research.
Our group is an international interdisciplinary team drawing its members from biology, physics, chemistry, computer science and engineering. The overarching theme of the lab is to understand the molecular mechanism of the nuclear division cycle in a comprehensive manner in the physiological context of the intact living cell. To achieve this we develop fluorescence-based imaging technologies to assay cellular functions non-invasively, automate imaging to address all molecular components and computationally process image data to extract biochemical and biophysical parameters in order to generate mechanistic understanding and predictive models. Our biological questions are currently focused on three areas.